Effects of continuous positive airway pressure on coagulability in obstructive sleep apnoea: a randomised, placebo-controlled crossover study

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منابع مشابه

Effects of continuous positive airway pressure on coagulability in obstructive sleep apnoea: a randomised, placebo-controlled crossover study.

INTRODUCTION Obstructive sleep apnoea (OSA) is associated with increased cardiovascular risk, however the mechanisms are not well established. OBJECTIVES This study aimed to determine whether treatment of OSA with nasal continuous positive airway pressure (CPAP) would favourably alter coagulability across the sleep-wake cycle. METHODS In a randomised crossover trial, 28 patients received th...

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Randomised controlled crossover trial of humidified continuous positive airway pressure in mild obstructive sleep apnoea.

BACKGROUND It is unclear whether continuous positive airway pressure (CPAP), the treatment of choice for severe obstructive sleep apnoea (OSA), is effective at improving outcomes in mild OSA. METHODS To help define the role of humidified CPAP in mild OSA, a randomised crossover study was undertaken of patients with an apnoea hypopnoea index (AHI) of 5-30/hour. Subjective sleepiness, objective...

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Cardiometabolic changes after continuous positive airway pressure for obstructive sleep apnoea: a randomised sham-controlled study.

RATIONALE AND OBJECTIVES Impaired insulin sensitivity (ISx), increased visceral abdominal fat (VAF) and liver fat are all central components of the metabolic syndrome and characteristics of men with obstructive sleep apnoea (OSA). The reversibility of these observed changes with continuous positive airway pressure (CPAP) treatment in men with OSA has not been systematically studied in a randomi...

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SLEEP DISORDERED BREATHING Randomised controlled crossover trial of humidified continuous positive airway pressure in mild obstructive sleep apnoea

Background: It is unclear whether continuous positive airway pressure (CPAP), the treatment of choice for severe obstructive sleep apnoea (OSA), is effective at improving outcomes in mild OSA. Methods: To help define the role of humidified CPAP in mild OSA, a randomised crossover study was undertaken of patients with an apnoea hypopnoea index (AHI) of 5–30/hour. Subjective sleepiness, objective...

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Humidified nasal continuous positive airway pressure in obstructive sleep apnoea.

Heated humidification of nasal continuous positive airway pressure (nCPAP) reduces upper airway symptoms and improves initial use in obstructive sleep apnoea syndrome (OSAS). The present study aimed to assess the effect of heated humidification of nCPAP on upper airway symptoms and initial use in obstructive sleep apnoea. This study was of a randomised, crossover design. Subjects with polysomno...

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ژورنال

عنوان ژورنال: Thorax

سال: 2012

ISSN: 0040-6376,1468-3296

DOI: 10.1136/thoraxjnl-2011-200874